1. Compiler-Based Real Chemistry for Smarter Synthesis: 

• Utilized advanced algorithms to design and optimize chemical reactions. 
• Defined detailed reaction roles, tags, and condition templates to enhance the specificity and relevance of synthesis operations. 

2. Intelligent Condition Optimization: 

• Developed a robust solution to optimize reaction conditions, including the required amounts and concentrations of reactants and reagents. 
• Implemented condition templates that could be reused and adjusted for different synthesis processes, ensuring high yields and purity. 

3. Centralized Registration and Inventory Integration: 

• Integrated with Mosaic and other inventory systems to manage the inventory of reactants, solvents, and agents. 
• Automated inventory checks to ensure the availability of necessary components before initiating synthesis. 
  
• Leveraged automated worklist generation to create detailed instructions for liquid handling devices, optimizing pipetting techniques and scheduling tasks seamlessly. 

4. Streamlined Workflows for Online and Offline Execution: 

• Supported both automated (online) and manual (offline) execution modes for library synthesis. 
• Provided tools for real-time monitoring of tasks, capturing progress, and reporting errors to ensure efficient task management. 

5. Post-Synthesis Workflows for Quality Assurance: 

• Defined workflows for subsequent processing, including purity checks and MS affinity tests. 
• Configured worklists for post-synthesis activities to ensure smooth transitions between different stages of the synthesis process. 

1. Scalable & High-Quality Synthesis and Registration: 

• Successfully synthesized and registered over 18,000 compounds, significantly expanding the chemical library. 
• Achieved high yields and purity of synthesized molecules through optimized conditions. 

2. Improved Operational Efficiency: 

• Reduced manual tasks and minimized the potential for human error through automated worklist generation and real-time monitoring. 
• Enhanced the productivity of researchers by allowing them to focus on critical scientific endeavors rather than manual data entry and process management. 
  
• Streamlined workflows enabled faster and more efficient synthesis processes, reducing turnaround times for compound creation. 

• Integration with inventory systems ensured the availability of all necessary components, reducing delays due to shortages. 
  
• Automated inventory checks and updates improved the accuracy and efficiency of inventory management, ensuring that reactants and reagents were always available when needed. 

4. Efficient Data Transfer to LIMS: 

• Data from the synthesis process was efficiently transferred to the LIMS, ensuring that all synthesized compounds were accurately recorded and available for further analysis. 
• Enhanced data accuracy and consistency through automated data capture and transfer processes, reducing the risk of errors in data entry and improving the reliability of records. 

5. Customizability and Scalability: 

• The synthesis process was tailored to meet specific research requirements, demonstrating the flexibility of Project JedAI’s solutions. 
• Processes were scaled to accommodate varying project sizes, from small-scale experiments to large-scale library synthesis projects, showcasing the scalability of the implemented strategies.